Saturday, 22 December 2018

What is the solubility data as per any Pharmacopoeia?


Different products have different solubility levels. The solubility of the product is determined by dissolving in know volume of solvent.
  •  Approximately volume of solvent in ml per gram of solute at 20° to 30°C
  • Very soluble : Less than 1
  • Freely soluble : From 1 to 10
  • Soluble : From 10 to 30
  • Sparingly soluble : From 30 to 100
  •  Slightly soluble : From 100 to 1000
  •  Very slightly soluble : From 1000 to 10000
  • Insoluble / practically soluble : More than 10000

 Example:  Very soluble means one gram of solute substance will require less than 1 ml of solvent.

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